387 – From farm management to bacteriophage therapy strategies to reduce antibiotic use (Research paper – Kahn – 2019)

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387 Research paper – Kahn – 2019 – From farm management to bacteriophage therapy strategies to reduce antibiotic use

Specific alternatives \ Immunomodulators

Species targeted: Pigs; Poultry; Dairy; Beef; Sheep;
Age: Different for different species;
A number of effective or commercially viable alternatives have been implemented to reduce the use of antibiotics in livestock. The most well-established strategies are flock and herd management practices to mitigate disease introduction and spread, and, subsequently, reduce the need for antibiotic use. While vaccines in food animal production have been used to prevent both bacterial and viral diseases, but historically, most vaccines have targeted viral diseases. Though vaccines against viral diseases can help reduce the need for antibiotic use by controlling the spread of secondary bacterial infections, more recent vaccines under development specifically target bacteria. New developments in selecting and potentially tailoring bacteriophages provide a promising avenue for controlling pathogenic bacteria without the need for traditional small-molecule antibiotics. In this article we discuss these established and emerging strategies, which are anticipated to reduce the reliance on antibiotics in food animal production and should reduce the prevalence and transmission to humans of antimicrobial resistant bacteria from these systems.

Where to find the original material: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850639/; 10.1111/nyas.14034

Country: Canada, New York