390 – Phytochemicals as antibiotic alternatives to promote growth and enhance host health (Research paper – Lillehoj – 2018)

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390 Research paper – Lillehoj – 2018 – Phytochemicals as antibiotic alternatives to promote growth and enhance host health

In Significant Impact Groups: Feed / gut health \ Feed additives and supplements
Species targeted: Pigs; Poultry; Dairy;
Age: Not stated;
Summary:
Scientists from industry and academia and government research institutes shared their experience in developing and applying potential antibiotic-alternative phytochemicals commercially to reduce AGPs and to develop a sustainable animal production system in the absence of antibiotics.

Where to find the original material: https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-018-0562-6; 10.1186/s13567-018-0562-6
Country: USA

389 – Alternatives to antibiotics for farm animals (Research paper – Papatsiros – 2014)

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389 Research paper – Papatsiros – 2014 – Alternatives to antibiotics for farm animals

In Significant Impact Groups: Specific alternatives \ Immunomodulators
Species targeted: Sheep; Dairy; Poultry; Pigs;
Age: Not stated;
Summary:

Nowadays, there is an increasing concern for the public health about the consequences from the long and increased use of antibiotics in livestock production. The use of antibiotics in animal feed as growth promoters has been completely banned by the European Union since 2006, based on their possible negative effects on human and animal health. The removal of growth promoters has led to animal performance problems and a rise in the incidence of certain animal diseases. Thus, there is an urgent need to find alternatives to antibiotics, especially in EU. Due to the modern consumers’ concern about the potential development of antibiotic-resistant bacteria as well as at the same time the need to prevent economic losses of the farmers, alternatives to antibiotics has been developed to prevent the health problems and to improve the growth performance in farm animals. Owing to the full ban of antibiotic use in EU there is an urgent need to find alternatives to in-feed antibiotics. New strategies and commercial products must be developed to improve animal health and performance, based on their safety, efficacy and cost-effectiveness. The aim of this study is to summarize the beneficial effects of currently used alternatives to in-feed antibiotics, i.e. probiotics, prebiotics, organic acids, phytogenic compounds and zeolites on health and growth performance in farm animals (swine, poultry and ruminants).

Where to find the original material: https://www.cabi.org/cabreviews/review/20133390413; 10.1079/PAVSNNR20138032
Country: Europe

388 – Veterinary use of bacteriophage therapy in intensively-reared livestock (Research paper – Gigante – 2019)

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388 Research paper – Gigante – 2019 – Veterinary use of bacteriophage therapy in intensively-reared livestock

In Significant Impact Groups: Specific alternatives \ Immunomodulators
Species targeted: Pigs; Poultry;
Age: Not stated;
Summary:
Zoonoses are infectious diseases transmitted directly or indirectly between animals and humans. Several important zoonotic pathogens colonize farm animals asymptomatically, which may lead to contamination of the food chain and public health hazards. Moreover, routine sampling of carcasses at retail by government authorities over the past 20 years suggests the prevalence of antibiotic resistance in foodborne pathogens has increased. If this continues, antibiotics may be ineffective against such pathogens in the future and alternative approaches, such as phage therapy, may be necessary. Intensive livestock farming is the only realistic way of meeting the demand for meat from an increasing global population and growth in middle class consumers in developing countries, particularly in Asia. This review elaborates on the use of phages to control zoonotic pathogens in intensively-reared livestock (poultry and pigs).

Where to find the original material: https://virologyj.biomedcentral.com/articles/10.1186/s12985-019-1260-3; 10.1186/s12985-019-1260-3
Country: UK

387 – From farm management to bacteriophage therapy strategies to reduce antibiotic use (Research paper – Kahn – 2019)

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387 Research paper – Kahn – 2019 – From farm management to bacteriophage therapy strategies to reduce antibiotic use

Specific alternatives \ Immunomodulators

Species targeted: Pigs; Poultry; Dairy; Beef; Sheep;
Age: Different for different species;
Summary:
A number of effective or commercially viable alternatives have been implemented to reduce the use of antibiotics in livestock. The most well-established strategies are flock and herd management practices to mitigate disease introduction and spread, and, subsequently, reduce the need for antibiotic use. While vaccines in food animal production have been used to prevent both bacterial and viral diseases, but historically, most vaccines have targeted viral diseases. Though vaccines against viral diseases can help reduce the need for antibiotic use by controlling the spread of secondary bacterial infections, more recent vaccines under development specifically target bacteria. New developments in selecting and potentially tailoring bacteriophages provide a promising avenue for controlling pathogenic bacteria without the need for traditional small-molecule antibiotics. In this article we discuss these established and emerging strategies, which are anticipated to reduce the reliance on antibiotics in food animal production and should reduce the prevalence and transmission to humans of antimicrobial resistant bacteria from these systems.

Where to find the original material: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850639/; 10.1111/nyas.14034

Country: Canada, New York

386 – Eficacitatea probioticelor în tratamentul gastroenteropatiilor la puii broiler (Research paper – Balanescu – 2017)

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386 Research paper – Balanescu – 2017 – Eficacitatea probioticelor în tratamentul gastroenteropatiilor la puii broiler

In Significant Impact Groups: Feed / gut health \ Feed additives and supplements
Species targeted: Poultry;
Age: Young;
Summary:
An experiment using broiler chickens (Ros-308) was conducted to assess the influence of the commercial preparation Rescue Kit SL (containing Bacillus licheniformis and Bacillus subtilis, betaine, vitamins and microelements), administered in the drinking water (1g/litre) from the age of 9 to 14 days. One group that was not given the additive, was considered as control. Performance indices were measured weekly and blood samples were collected from 14, 35 and 50-d-old chicks for biochemical and hematological analyses. The results indicate a reduced lethality rate in experimental group – 3.5%, while 3.9% (control). At the end of the production cycle (50 days) the body weight was by 50 g higher in broiler chickens from the experimental group. The preparation Rescue Kit SL induced the increase of erythrocytes, hemoglobin, total protein and glucose in blood serum.
386 Research paper – Balanescu – 2017 – Eficacitatea probioticelor în tratamentul gastroenteropatiilor la puii broiler
https://sa.

Where to find the original material: https://sa.uasm.md/index.php?journal=sa&page=article&op=view&path%5B%5D=117;
Country: MD

385 SUINLACT – bioaditiv furajer utilizat in alimentatia suinelor by IBNA (Industry Innovation)

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385 Industry Innovation – SUINLACT – bioaditiv furajer utilizat in alimentatia suinelor by IBNA

In Significant Impact Groups: Feed / gut health \ Feed additives and supplements
Species targeted: Pigs;
Age: Young; Adult;
Summary:
SUINLACT is a feed bioadditive based on polyculture with selected strains of lactic acid bacteria that produce lactic acid and some bacteriocins and counterfeit to prevent and control enterocolitis in pigs by populating the digestive tract with these health-friendly bacteria.

Where to find the original material: https://www.ibna.ro/pdf/SUINLACT-pliant-2008-1.pdf;
Country: RO

384 Cum îmbunătățesc fermierii îngrășarea porcilor cu ajutorul secarei by KWS (Farm Innovation)

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384 Farm Innovation – Cum îmbunătățesc fermierii îngrășarea porcilor cu ajutorul secarei by KWS

In Significant Impact Groups: Feed / gut health \ Feed composition
Species targeted: Pigs;
Age: Young; Adult;
Summary:
Successful fattening of pigs and animal welfare – Andreas von Felde believes that these objectives are not excluded. This farmer from northern Germany grows rye and uses it as feed. He says he needs less fertilizer.
“Rye has a large amount of carbohydrates that are not digested in the small intestine. In short, they feed microorganisms in the small intestine and microflora. ” This produces butyric acid, which has a positive influence on the behavior of animals when they are fattened. Butyric acid is also very effective in killing bacteria such as salmonella.

Where to find the original material: https://www.kws.com/ro/ro/companie/presa/lumea-agricola/secara-in-hrana-porcilor/;
Country: DE

383- Natural alternatives to in-feed antibiotics in pig production (Research paper – Gallois – 2009)

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383 Research paper – Gallois – 2009 – Natural alternatives to in-feed antibiotics in pig production

In Significant Impact Groups: Feed / gut health \ Feed additives and supplements
Species targeted: Pigs;
Age: Adult; Young;
Summary:
The development of both innate and adaptive immunity at the mucosal surface is critical in preventing the potential harmful effects of intestinal pathogenic agents. Strategies aiming at stimulating natural host defences through the use of substances able to modulate immune functions have gained increasing interest in animal research, and different bioactive components a priori sharing those properties have been the subject of in vivo nutritional investigations in pig. Among these, yeast derivates (b-glucans and mannans) are able to interact with immune cells, particularly phagocytic cells. This review also highlights the limitations of some of the published in vivo studies on the immunomodulatory activity of certain feed additives. Among those, the lack of standardisation of extracts and the heterogeneity of piglet-rearing conditions (e.g. exposure to pathogens) are likely the most limiting.

Where to find the original material: https://www.researchgate.net/publication/221972346_Natural_alternatives_to_in-feed_antibiotics_in_pig_production_Can_immunomodulators_play_a_role; 10.1017/S1751731109004236

Country: France; Germany

382- Alternatives to antibiotics as growth promoters for use in swine production – A review (Research paper – Thacker – 2013)

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382 Research paper – Thacker – 2013 – Alternatives to antibiotics as growth promoters for use in swine production_ a review

In Significant Impact Groups: Specific alternatives \ Other
Species targeted: Pigs;
Age: Different for different species;
Summary:
The potential of antimicrobial peptides, clay minerals, egg yolk antibodies, essential oils, eucalyptus oil-medium chain fatty acids, rare earth elements and recombinant enzymes are discussed on the above review. Based on a thorough review of the literature, it is evident that a long and growing list of compounds exist which have been tested for their ability to replace antibiotics as feed additives in diets fed to swine.

Where to find the original material: https://jasbsci.biomedcentral.com/articles/10.1186/2049-1891-4-35; 10.1186/2049-1891-4-35
Country: Global

381- Effects of dietary hop B-acids or colistin on the performance nutrient digestibility and intestinal health of weanling pigs (Research paper – Sbardellaa – 2016)

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381 Research paper – Sbardellaa – 2016 – Effects of dietary hop B-acids or colistin on the performance nutrient digestibility and intestinal health of weanling pigs

In Significant Impact Groups: Prudent use AB \ Farmer
Species targeted: Pigs;
Age: Young;
Summary:
Colistin is still often used outside the European Union as antibiotics to improve animal performance and health. Because first signs on antimicrobial resistance for colistin are seen, the scientific world is urgently looking for replacement of colistin as well as to find substitutes for zinc oxide in the European Union. Hops, known for their interactions with microbial cell structures, can offer a solution. This article describes and benchmarks hop extracts (β-acids) for that purpose, and came to interesting findings. When applied in nutrition for piglets, they observed improved performance (daily weight gain, daily feed conversion ratio), mainly by improved nutrient digestibility and intestinal health.

Where to find the original material: https://www.sciencedirect.com/science/article/abs/pii/S0377840116301420?via%3Dihub; http://dx.doi.org/10.1016/j.anifeedsci.2016.04.007
Country: BR