350 Effects of methylsulfonylmethane (Research paper Abdul Rasheed, 2020)

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350 Research paper Abdul Rasheed 2020 Effects of methylsulfonylmethane

In Significant Impact Groups: Pathogen management \ Eradication; Feed / gut health
Species targeted: Poultry;
Age: Young;
Summary:
This experiment showed promising results in the recovery of broiler chicks after a challenge with mild coccidiosis infection (E. Tenella). The chicks were fed a feed containing an additive that boosted their immuneresponse to the parasite and an additional antioxidant to mitigate tissue damage to the gut from an excessive immune response. Both the chicks on the control diet (without the new additives) and the chicks receiving the treatment were challenged with a mild coccidiosis infection and did not differ in overall performance. However, the chicks on the treatment diet showed faster recovery and better daily gain instantely after the infection with the parasite. This led the researchers to believe that chicks under a more severe infection could benefit more from this innovative dietary supportive treatment.

Where to find the original material: https://www.sciencedirect.com/science/article/pii/S0032579120306982; https://doi.org/10.1016/j.psj.2020.09.046
Country: USA

346 – Genome editing for disease resistance in pigs and chickens (Research paper – Proudfoot – 2019)

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346 Research paper – Proudfoot – 2019 – Genome editing for disease resistance in pigs and chickens

In Significant Impact Groups: Breeding for disease resistance or robustness
Species targeted: Pigs; Poultry;
Age: Not stated;
Summary:
Targeted breeding is common practice, with measurable production traits such as feed conversion in cattle or wool production in sheep. In the late 20th century, genomic selection was added to the livestock breeding tool box achieving faster improvement in livestock production efficiency. Genome editing offers new opportunities to livestock breeding for disease resistance, allowing the direct translation of laboratory research into disease-resistant or resilient animals. Shown progress in genome editing so far in pigs and chicken are discussed (PRRS, PEDV, ASFV and ALV, avian influenza virus).The two major hurdles still to be faced prior to implementation of this promising technology are consumer acceptance and the regulatory framework.

Where to find the original material: https://academic.oup.com/af/article/9/3/6/5522878; https://doi.org/10.1093/af/vfz013
Country: UK

344 – Usage of Antibiotics in Agricultural Livestock in the Netherlands in 2017 Trends and benchmarking of livestock farms and veterinarians (Research report – Sda – 2018)

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344 Research report – Sda – 2018 – Usage of Antibiotics in Agricultural Livestock in the Netherlands in 2017 Trends and benchmarking of livestock farms and veterinarians

In Significant Impact Groups: AMU reduction strategies \ Monitoring and surveillance; Antibiotic use
Species targeted: Pigs; Poultry; Dairy; Beef; Other;
Age: Different for different species;
Summary:
In 2017, the turkey and broiler farming sectors managed to substantially reduce their antibiotic use in terms of defined daily doses animal (DDDANAT). They achieved reductions of 23.7% and 7.8%, respectively. Less prominent reductions of 3.6% and 1.9% were observed for the veal and pig farming sectors, respectively. The cattle farming sector’s usage level increased slightly over the 2016-2017 period, by 2.2%. In 2017, no distinct shifts towards lower benchmark zones occurred in the veal farming sector. The pig farming sector saw an undesirable rise in the percentage of farms with weaner pigs recording action zone usage levels. This development was due to the new benchmark thresholds introduced in 2016.The SDa expert panel recommends paying special attention to outlier farms. In 2017, sales of antibiotics in terms of kilograms of active substances amounted to 181,097 kg.

Where to find the original material: https://www.autoriteitdiergeneesmiddelen.nl/en/news/28/sda-report-usage-of-antibiotics-in-agricultural-livestock-in-the-netherlands-in-2017 ;
Country: NL

343 – Associations between antimicrobial use and the prevalence of resistant micro-organisms Is it possible to benchmark livestock farms based on resistance data (Research report – Sda – 2016)

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343 Research report – Sda – 2016 – Associations between antimicrobial use and the prevalence of resistant micro-organisms Is it possible to benchmark livestock farms based on resistance dat

In Significant Impact Groups: AMU reduction strategies \ Monitoring and surveillance; Antibiotic use
Species targeted: Pigs; Poultry; Beef;
Age: Young;
Summary:
An expert panel analyzed the relationship between antimicrobial use in the Dutch livestock sector and the prevalence of antimicrobial-resistant micro-organisms in livestock. Changes in usage and resistance levels between 2009 and 2014, for most of the commonly used antibiotics, the strongest declines in usage levels were observed in the pig (54%) and broiler (57%) farming sectors. In most livestock sectors, total and antimicrobial-specific usage levels are clearly associated with the antimicrobial-specific resistance levels. Is it possible to benchmark livestock farms based on resistance data? This would require information on resistance-related risks such as public health risks, and currently available data do not allow for quantification of such risks. If an acceptable resistance level were to be determined, the corresponding antimicrobial usage level could serve as the basis for benchmarking values. As yet, however, no acceptable resistance level has been defined.

Where to find the original material: https://cdn.i-pulse.nl/autoriteitdiergeneesmiddelen/userfiles/Publications/def-engels-rapport-abgebruik-en-resistentie-0516.pdf;
Country: NL

339 – Economics of antibiotic usage on Dutch farms (Research report – Policy paper – Bergevoet – 2019)

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339 Research report – Bergevoet – 2019 – Policy paper_ Economics of antibiotic usage on Dutch farms

In Significant Impact Groups: Other
Species targeted: Pigs; Poultry;
Age: Not stated;
Summary:
Dutch Policy Paper. Reduction in antibiotic usage did not lead to a weaker competitive position of Dutch farmers. The reduction in antibiotic usage on broiler and pig farms in the Netherlands from 2009 to 2017 did not result in a deviation from the long-term trend in average production and economic results in these sectors. To improve animal health, which made a reduction in antibiotic usage possible, farmers used a variety of relatively easy and cheap measures, such as more attention to hygiene, use of pain killers and anti-inflammatory agents or more preventive vaccinations. International cost competitiveness of Dutch broiler and pig farms was not hampered by the reduction in antibiotic usage. The deterioration of the cost competitiveness in especially sow farms was caused by other factors, e.g. an increase of environmental costs. Experiences in the Netherlands show that an active policy towards antibiotic usage reduction can work.

Where to find the original material: https://research.wur.nl/en/publications/economics-of-antibiotic-usage-on-dutch-farms-the-impact-of-antibi;
Country: NL

330 – Factors potentially linked with the occurrence of antimicrobial resistance in selected bacteria from cattle chickens and pigs – A scoping review (Research paper – Murphy – 2018)

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330 Research paper – Murphy – 2018 – Factors potentially linked with the occurrence of antimicrobial resistance in selected bacteria from cattle chickens and pigs_A scoping review

In Significant Impact Groups: Other
Species targeted: Pigs; Poultry; Beef;
Age: Young; Adult;
Summary:
Antimicrobial resistance is a complex issue with a large volume of published literature, and there is a need for synthesis of primary studies for an integrated understanding of this topic. A comprehensive literature search and screening were performed to identify studies investigating factors potentially linked with antimicrobial resistance in Campylobacter species, Escherichia coli and Salmonella enterica along the farm‐to‐fork pathway (farm, abattoir (slaughter houses) and retail meats) for the major Canadian livestock species (beef cattle, broiler chicken and pigs). The most common factors identified were antimicrobial use and type of farm management system (e.g., antibiotic‐free, organic). There are still insufficient research done on the effect of vaccination, industry‐specific factors (e.g., livestock density) and factors at sites other than farm along the agri‐food chain. Further investigation of these factors and other relevant industry activities are needed in order to identify effective interventions to decrease antimicrobial resistance along the agri‐food chain.

Where to find the original material: https://onlinelibrary.wiley.com/doi/full/10.1111/zph.12515; https://doi.org/10.1111/zph.12515
Country: CA

327 – On-farm comparisons of different cleaning protocols in broiler houses (Research paper – Luyckx – 2015)

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327 Research paper – Luyckx – 2015 – On-farm comparisons of different cleaning protocols in broiler houses

In Significant Impact Groups: Biosecurity
Species targeted: Poultry;
Age: Young;Adult;
Summary:
The present study evaluated the effectiveness of 4 cleaning protocols designed to reduce the bacteriological infection pressure on broiler farms and prevent food-borne zoonoses. Additionally, difficult to clean locations and possible sources of infection were identified. Cleaning and disinfection rounds were evaluated in by sampling 12 broiler houses on 5 farms. Bacterial counts counts on the swab samples showed that cleaning protocols which were preceded by an overnight soaking with water caused a higher bacterial reduction compared to protocols without a preceding soaking step. Moreover, soaking of broiler houses leads to less water consumption and reduced working time during high pressure cleaning. No differences were found between protocols using cold or warm water during cleaning. Drinking cups, drain holes, and floor cracks were identified as critical locations for cleaning and disinfection in broiler houses.

Where to find the original material: https://www.sciencedirect.com/science/article/pii/S0032579119322308; https://doi.org/10.3382/ps/pev143
Country: BE

326 – Vaccines as alternatives to antibiotics for food producing animals Part 2 (Research paper – Hoelzer – 2018)

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326 Research paper – Hoelzer – 2018 – Vaccines as alternatives to antibiotics for food producing animals Part 2

In Significant Impact Groups: Pathogen management \ Vaccination; Specific alternatives
Species targeted: Pigs; Poultry; Dairy; Beef; Sheep; Other;
Age: Young; Adult;
Summary:
This article highlights new approaches and potential solutions for the development of vaccines as alternatives to antibiotics in food producing animals. Many current vaccines fall short of ideal vaccines in one or more respects. Promising breakthroughs to overcome these limitations include new biotechnology techniques, new oral vaccine approaches, novel adjuvants, new delivery strategies based on bacterial spores, and live recombinant vectors; they also include new vaccination strategies in-ovo, and strategies that simultaneously protect against multiple pathogens. However, translating this research into commercial vaccines that effectively reduce the need for antibiotics will require close collaboration among stakeholders, for instance through public–private partnerships. Targeted research and development investments and concerted efforts by all affected are needed to realize the potential of vaccines to improve animal health, safeguard agricultural productivity, and reduce antibiotic consumption and resulting resistance risks.

Where to find the original material: https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-018-0561-7?optIn=true; https://doi.org/10.1186/s13567-018-0561-7
Country: USA; UK; FR; BE; DE

325- Vaccines as alternatives to antibiotics for food producing animals Part 1 (Research paper – Hoelzer – 2018)

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325 Research paper – Hoelzer – 2018 – Vaccines as alternatives to antibiotics for food producing animals Part 1

In Significant Impact Groups: Pathogen management \ Vaccination; Specific alternatives
Species targeted: Pigs; Poultry; Dairy; Beef; Sheep;
Age: Young; Adult;
Summary:
Vaccines and other alternative products can help minimize the need for antibiotics by preventing and controlling infectious diseases in animal populations, and are central to the future success of animal agriculture. This article, synthesizes and expands on the expert panel discussions regarding opportunities, challenges and needs for the development of vaccines that may reduce the need for use of antibiotics in animals. Vaccines are widely used to prevent infections in food animals. Various studies have demonstrated that their animal agricultural use can lead to significant reductions in antibiotic consumption, making them promising alternatives to antibiotics. To be widely used in food producing animals, vaccines have to be safe, effective, easy to use, and cost-effective. Although vaccines have the potential to improve animal health, safeguard agricultural productivity, and reduce antibiotic consumption and resulting resistance risks, targeted research and development investments and concerted efforts are needed to realize that potential.

Where to find the original material: https://link.springer.com/article/10.1186/s13567-018-0560-8; https://doi.org/10.1186/s13567-018-0560-8
Country: USA; UK; FR; BE; DE

324- Use of phytobiotics in broiler nutrition an alternative to infeed antibiotics (Research paper – Grashorn – 2010)

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324 Research paper – Grashorn – 2010 – Use of phytobiotics in broiler nutrition an alternative to infeed antibiotics

In Significant Impact Groups: Feed / gut health \ Feed additives and supplements; Specific alternatives
Species targeted: Poultry;
Age: Young; Adult;
Summary:
After the ban of antibiotic growth promoters (AGP) in the EU many alternative substances have been investigated for their potential to replace AGPs. Phytobiotics are discussed as one promising alternative due because they contain many pharmacologically active compounds. A huge number of studies have confirmed a wide range of activities of phytobiotics in poultry nutrition like stimulation of feed intake, antimicrobial, coccidiostatic and anthelmintic effects. The present paper gives a short review on the characteristics of phytobiotics, on the potential mode of action and on the effects of phytobiotics in diets on performance, carcass and meat quality and health status in broilers. Furthermore, it addresses possible safety concerns involving application of phytobiotics.
324

Where to find the original material: http://www.jafs.com.pl/Use-of-phytobiotics-in-broiler-nutrition-n-an-alternative-to-infeed-antibiotics-,66297,0,2.html; https://doi.org/10.22358/jafs/66297/2010
Country: DE