238 Research paper – Moreno – 2014 – Survey of quantitative antimicrobial consumption per production stage in farrow-to-finish pig farms in Spain

In Significant Impact Groups: AMU reduction strategies \ Monitoring and surveillance Antibiotic use
Species targeted: Pigs;
Age: Young; Adult;
Summary:
This study describes antimicrobial use (AMU) per production stage in terms of drugs, routes of application, indications, duration and exposed animals in farrow-to-finish pig farms in Spain. Information was collected via a questionnaire on AMU during the six months prior to the interview, in face-to-face interviews completed from April to October 2010, for a total of 49 farms. The most used antimicrobials per farm and production stage and administration route were polymyxins (colistin) by feed in the growing and the preweaning phases, followed by β-lactams by feed during the growing and the preweaning phases and by injection during the preweaning phase. Results show that the growing stage (from weaning to beginning of finishing) has the highest AMU, feed is the administration route with the highest antimicrobial exposure (because of high number of exposed animals and longer duration of treatment); and there are large differences in AMU among individual pig farms.

Where to find the original material: https://vetrecordopen.bmj.com/content/1/1/e000002.short; https://doi.org/10.1136/vropen-2013-000002
Country: ES

236 Research paper – Cameron-Veas – 2018 – Multidrug resistant Salmonella enterica isolated from conventional pig farms using antimicrobial agents in preventative medicine programme

In Significant Impact Groups: AMU reduction strategies \ Monitoring and surveillance Disease/health
Species targeted: Pigs;
Age: Young;
Summary:
Presence of multidrug antimicrobial resistance (multi-AR) in Salmonella enterica in pigs in Spain was investigated in this study, together with association of multi-drug resistance with ceftiofur or tulathromycin treatment during the pre-weaning period. Sixty-six S. enterica isolates were recovered from five of the eight farms studied. Forty-seven bacteria (isolates) were multi-drug resistant. The most frequent AR genes detected were tet(A) (77%), sul1 (26%); tet(B) (23%) and qnrB (66,15%). Multi-drug resistance was common, especially for ampicillin, streptomycin, sulphonamides and tetracycline. These antibiotics are used frequently in veterinary medicine in Spain and, therefore, should be used carefully to minimise the spread of multi-drug resistance.

Where to find the original material: https://www.sciencedirect.com/science/article/pii/S1090023318300339; https://doi.org/10.1016/j.tvjl.2018.02.002
Country: ES

231 Research paper – Miguela-Villoldo – 2019 – National colistin sales versus colistin resistance in Spanish pig production

In Significant Impact Groups: AMU reduction strategies \ Monitoring and surveillance; Antibiotic use
Species targeted: Pigs;
Age: Young; Adult;
Summary:
Antimicrobials, particularly colistin, have been the first choice to control a certain type pf bacteria (Gram-negative) in pig production, and often used preventively. However, colistin is now considered to be a last resort antibiotic in human clinical practice. In 2015, the colistin resistance gene (mcr-1) was discovered in China. This mcr-1 gene was then reported in Southern Europe in 2016 in bacteria from farm animals (poultry and pigs). Currently, eight mcr genes have been reported (mcr-1 to 8)). In 2016, the EMA (European Medicine Agency) aimed to reduce use of colistin in animals in the European Union and a voluntary strategic plan to reduce colistin use in pigs was introduced in Spain. A total of 70% of Spanish pig production companies joined the program, representing 80% of Spanish pig production. The impact of these recommendations in the colistin resistance levels in pigs in Spain is reported in this article.

Where to find the original material: https://pubmed.ncbi.nlm.nih.gov/30660816/; https://doi.org/10.1016/j.rvsc.2019.01.010
Country: ES