486 – Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks growths and foresight in swine production (Research paper – Adewole – 2016)

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486 Research paper – Lopes Antunes – 2019 – Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks growths and foresight in swine production

486 Research paper
Unweaving tangled mortality and antibiotic consumption data to detect disease outbreaks – Peaks, growths, and foresight in swine production by Lopes Antunes, A.C., Jensen, V.F., and D. Jensen 2019 PLoS One 14: e0223250
In Significant Impact Groups: Other
Species targeted: Pigs;
Age: Not stated;
Summary:
Monitoring systems are essential for detecting changes in disease status in a timely and effective manner. This is of paramount importance to reduce the impact of outbreaks and to avoid trade restrictions. The ability to detect changes in disease occurrence depends to a large extent upon the choice of data source. The increasing availability of electronic records collected actively or passively enables the targeting of specific groups and the monitoring and prediction of specific events. Monitoring changes in mortality data and antibiotic consumption showed changes at herd level prior to and in the same month as confirmation from diagnostic tests. These results also show a potential value for using these data streams as part of surveillance strategies.
Where to find the original material: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785175/pdf/pone.0223250.pdf; https://doi.org/10.1371/journal.pone.0223250
Country: DK

415 – The effects of supplementation of yeast Saccharomyces cere-visiae and postbiotic from Lactobacillus acidophilus on the health and growth performance (Research paper – Thorsteinsson – 2020)

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415 Research paper – Thorsteinsson – 2020 – The effects of supplementation of yeast Saccharomyces cere-visiae and postbiotic from Lactobacillus acidophilus on the health and growth performa

415 Research paper
The effects of supplementation of yeast (Saccharomyces cere-visiae) and postbiotic from Lactobacillus acidophilus on the health and growth performance of young Jersey heifer calves by Thorsteinsson, M., Martin, H.K., Larsen, T., Sehested, J. and M. Vestergaard 2020 Journal of Animal and Feed Sciences 29: 224-233
In Significant Impact Groups: Specific alternatives \ Pre-/probiotics
Species targeted: Dairy;
Age: Young;
Summary:
This research looked upon the possible effect of probiotica Zoolac Bovimix Milk fed to calves from birth until 4 weeks old. There were no effect on the health of the calves since both the control group and the experimental group had similar frequency of antibiotic treatments. However, the calves supplemented with the product containing probiotic and postbiotic had a significantly higher growth performance.
415 Research paper – Thorsteinsson – 2020 – The effects of supplementation of yeast Saccharomyces cere-visiae and postbiotic from Lactobacillus acidophilus on the health and growth performance of young Jersey heifer calves
Where to find the original material: https://doi.org/10.22358/jafs/127447/2020
Country: DK

412 Probiotica by Aarhus Universitet (Farm Innovation)

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412 Farm Innovation – Probiotica by Aarhus Universitet

412 Farm Innovation
Probiotica by Aarhus Universitet
In Significant Impact Groups: Specific alternatives \ Pre-/probiotics
Species targeted: Dairy; Beef;
Age: Young;
Summary:
The article describes as probiotica tested in calves from 4 weeks to 10 weeks old. The calves in the test had a higher level of yeast cells in the intestines, but the insidens of diarrhea was low in both calves fed the probiotic and in calves with out. They have tested 150 calves from 0-4 weeks but the results are not accessible yet.
412 Farm Innovation – Probiotica by Aarhus Universitet
Where to find the original material: https://www.maskinbladet.dk/artikel/108769_probiotika-produkt-har-vist-lovende-resultater-med-kalve;
Country: DK

411 – Passive immunisation an old idea revisited – Basic principles and application to modern animal production systems (Research paper – Hedegaard – 2016)

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411 Research paper – Hedegaard – 2016 – Passive immunisation an old idea revisited_ Basic principles and application to modern animal production systems

411 Research paper
Passive immunisation, an old idea revisited: Basic principles and application to modern animal production systems by Hedegaard C.J. and P.M.H. Heegaard
2016 Veterinary Immunology and Immunopathology Volume 174: 50-63
In Significant Impact Groups: Prudent use AB \ Veterinarian
Species targeted: Pigs; Poultry; Dairy; Beef; Sheep;
Age: Adult;
Summary:
Immunisation by administration of antibodies (immunoglobulins) has been known for more than one hundred years as a very efficient means of obtaining immediate, short-lived protection against infection and/or against the disease-causing effects of toxins from microbial pathogens and from other sources. This review highlights a number of examples on the use of passive immunisation for the control of infectious disease in the modern production of a range of animals, including pigs, cattle, sheep, goat, poultry and fish. It is concluded that provided highly efficient, relatively low-price immunoglobulin products are available, passive immunisation has a clear role in the modern animal production sector as a means of controlling infectious diseases, importantly with a very low risk of causing development of bacterial resistance, thus constituting a real and widely applicable alternative to antibiotics.
411 Research paper – Hedegaard – 2016 – Passive immunisation an old idea revisited_ Basic principles and application to modern animal production systems

Where to find the original material: https://www.sciencedirect.com/science/article/abs/pii/S0165242716300642?via%3Dihub; https://doi.org/10.1016/j.vetimm.2016.04.007
Country: Denmark

371- Practical strategies to reduce antimicrobial use in dairy farming (Research report – EuroDairy – 2018)

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371 Research report – EuroDairy – 2018 – Practical strategies to reduce antimicrobial use in dairy farming

In Significant Impact Groups: AMU reduction strategies \ None
Species targeted: Dairy;
Age: Adult; Young;
Summary:
This report highlights the extent of quantitative reduction which can be achieved, both in overall antimicrobial use, and especially of Critically Important Antibiotics (CIA’s) whose efficacy must be preserved for use in human medicine. EuroDairy gathered intelligence through its partners and wider networks, organized a cross border workshop, farmer exchange visits, technical webinars, and linked to regional Operational Groups focussed on reducing antibiotics. The only way to sustainably reduce the risk of Antimicrobial Resistance (AMR) is through an integrated approach to disease control, which sustainably improves animal health. Hotspots for antibiotic use are treatment for mastitis (including dry cow therapy), lameness and foot health, respiratory disease and young stock health.

Where to find the original material: https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5c0d054f7&appId=PPGMS;
Country: SE; DK; NL; UK; BE; FR; ES

336- Quantitative and qualitative analysis of antimicrobial usage patterns in 180 selected farrow-to-finish pig farms from nine European countries (Research paper – Sarrazin – 2018)

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336 Research paper – Sarrazin – 2018 – Quantitative and qualitative analysis of antimicrobial usage patterns in 180 selected farrow-to-finish pig farms from nine European countries

In Significant Impact Groups: Other
Species targeted: Pigs;
Age: Young;
Summary:
Objectives: Farm-level quantification of antimicrobial usage (AMU) in pig farms.
Methods: In a cross-sectional study, AMU data on group treatments administered to a single batch of fattening pigs from birth to slaughter (group treatment data) and antimicrobials purchased during 1 year (purchase data) were collected at 180 pig farms in nine European countries. AMU was quantified using treatment incidence (TI) based on defined (DDDvet) and used (UDDvet) daily doses and defined (DCDvet) and used (UCDvet) course doses.
Results: The majority of antimicrobial group treatments were administered to weaners (69.5% of total TIDDDvet) followed by sucklers (22.5% of total TIDDDvet). AMU varied considerably between farms with a median TIDDDvet of 9.2 and 7.1 for a standardized rearing period of 200 days based on group treatment and purchase data, respectively. In general, UDDvet and UCDvet were higher than DDDvet and DCDvet, respectively, suggesting that either the defined doses were set too low or that group treatments were often dosed too high and/or administered for too long. Extended-spectrum penicillins (31.2%) and polymyxins (24.7%) were the active substances most often used in group treatments, with the majority administered through feed or water (82%). Higher AMU at a young age was associated with higher use in older pigs.
Conclusions: Collecting farm-level AMU data of good quality is challenging and results differ based on how data are collected (group treatment data versus purchase data) and reported (defined versus used daily and course doses).

Where to find the original material: https://pubmed.ncbi.nlm.nih.gov/30544242/; https://doi.org/10.1093/jac/dky503
Country: BE, BG, DK, FR, DE, IT, PL, ES, NL

332- Danish Stable Schools for Experiential Common Learning in Groups of Organic Dairy Farmers (Research paper – Vaarst – 2007)

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332 Research paper – Vaarst – 2007 – Danish Stable Schools for Experiential Common Learning in Groups of Organic Dairy Farmers

In Significant Impact Groups: Prudent use AB \ Farmer
Species targeted: Dairy;
Age: Young; Adult;
Summary:
The farmer field school (FFS) is a concept for farmers’ learning, knowledge exchange, and empowerment. In Denmark, a research project focusing on explicit nonantibiotic strategies involves farmers who have actively expressed an interest in phasing out antibiotics from their herds through promotion of animal health. An FFS approach was adapted to Danish conditions and named “stable schools.” A facilitator was connected to each group whose role was to write the meeting agenda together with the host farmer, direct the meeting, and write the minutes to send to the group members after the meeting. Complex farming situations were the focus of all groups and in this context, problems were identified and solutions proposed based on each farmer’s individual goals. In this article, we describe the experiences of 4 stable school groups (each comprising farmers and a facilitator), and the process of building a concept suitable for Danish organic dairy farming.

Where to find the original material: https://www.sciencedirect.com/science/article/pii/S0022030207717526; https://doi.org/10.3168/jds.2006-607
Country: DK

212 – Temporal Relationship Between Decrease in Antimicrobial Prescription for Danish Pigs and the Yellow Card Legal Intervention Directed at Reduction of Antibiotics (Research paper – Jensen – 2014)

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212 Research paper – Jensen – 2014 – Temporal Relationship Between Decrease in Antimicrobial Prescription for Danish Pigs and the Yellow Card Legal Intervention Directed at Reduction of A

In Significant Impact Groups: Prudent use AB \ Veterinarian; AMU reduction strategies
Species targeted: Pigs;
Age: Not stated;
Summary:
The potential effects of the Yellow Card intervention, enforced by Danish authorities since 2010 on the antimicrobial prescription in the Danish pig production were investigated. Descriptive analysis of temporal trends in quantitative antimicrobial prescription for pigs were performed for each administration route, age and disease group. There was a 25% decline in the total antimicrobial use per pig produced between 2009 and 2011, both in sows, piglets, weaners and finishers. Reduced prescription of some antibiotics for oral use in weaners and finishers explained 76% of the total reduction. In 2012, the overall antimicrobial use increased by 10%, as a result of slight changes of prescription patterns. On herd level, the decline and subsequent increase was mainly related to changes in number of herds receiving regular monthly prescriptions. The steep decrease in antimicrobial use in the Danish pig production was temporally related with the announcement and introduction of the Yellow Card intervention.

Where to find the original material: https://pubmed.ncbi.nlm.nih.gov/25263135/; https://doi.org/10.1016/j.prevetmed.2014.08.006
Country: DK

198 – Reduced use of antimicrobials after vaccination of pigs against porcine proliferative enteropathy in a Danish SPF herd (Research paper – Bak – 2009)

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198 Research paper – Bak – 2009 – Reduced use of antimicrobials after vaccination of pigs against porcine proliferative enteropathy in a Danish SPF herd

In Significant Impact Groups: AMU reduction strategies \ Pathogen management
Species targeted: Pigs;
Age: Young;
Summary:
The present study explored whether the use of group medication with antibiotics in a Danish pig herd was reduced after vaccination of the pigs against proliferative enteropathy (PE) caused by Lawsonia intracellularis. 7900 pigs originating from a single commercial sow herd were vaccinated against L. intracellularis, whereas 7756 pigs were kept as non-vaccinated controls. The pigs were included batch-wise in the study with every second batch being vaccinated. In the vaccinated batches, the consumption of oxytetracykline to treat PE was reduced by 79%, with a significantly lower number of pigs being treated. Vaccination also resulted in a highly significant improvement of average daily weight gain (+ 46 g/day) and carcass weight (+ 1.25 kg) as well as a shortened fattening period (-8 days).

Where to find the original material: https://actavetscand.biomedcentral.com/articles/10.1186/1751-0147-51-1; https://doi.org/10.1186/1751-0147-51-1
Country: DK

197 – A register-based study on associations between vaccination antimicrobial use and productivity in conventional Danish finisher pig herds (Research report – Brinch – 2019)

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197 Research report – Brinch – 2019 – A register-based study on associations between vaccination antimicrobial use and productivity in conventional Danish finisher pig herds

In Significant Impact Groups: Prudent use AB \ Pharmaceuticals; Pathogen management
Species targeted: Pigs;
Age: Young;
Summary:
Vaccination has been suggested as a strategy to prevent disease and minimise the need for antimicrobial treatments. The aim of this study was to assess the associations between data on vaccination, productivity and AMU in Danish finisher herds over a 4-year period. Finisher herds (N = 40–62) with register data on productivity (i.e. average daily weight gain, feed conversion rate, mortality and lean meat percentage) and data on prescriptions of antimicrobials measured in Animal Daily Doses/100 finishers/day as well as the proportion of parenteral AMU treatments out of all treatments (AMU-ratio) were included. Vaccination against PRRS and higher AMU for finishers were associated with increased lean meat percentage. Vaccination against PCV2, PRRS and APP were associated with higher levels of AMU, and vaccination against Lawsonia with a higher AMU-ratio. This may be explained as some farmers preferring to take action soon after observing disease problems.

Where to find the original material: https://www.sciencedirect.com/science/article/pii/S0167587718304574; https://doi.org/10.1016/j.prevetmed.2019.01.007
Country: DK